Application | Comment | Organism |
---|---|---|
medicine | in a female patient with pseudo-hermaphrodism caused by an androgen-producing adrenocortical tumor. The activities of 3beta-hydroxysteroid dehydrogenase 2 and CYP17 in the tumor tissue are higher than those in the normal tissue, whereas the activity of 17beta?hydroxysteroid dehydrogenase 3 is lower. The mRNA levels of 3beta-hydroxysteroid dehydrogenase 2 and CYP17 are higher and the levels of 17beta-hydroxysteroid dehydrogenase 3 and LH/hCG receptor are lower in the tumor tissue compared with those of the normal tissue | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal adenoma cell | - |
Homo sapiens | - |
adrenal gland | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
3beta-hydroxysteroid dehydrogenase 2 | - |
Homo sapiens |
HSD2 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | the mRNA level of the enzyme is higher in tumor tissue compared with those of the normal tissue | up |